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Bioactive Molecules

Sonidegib CAS:956697-53-3

Sonidegib  CAS:956697-53-3


Product Information

CAS NO.956697-53-3 2.png
Product NameSonidegib
Molecular Weight485.49
Spec / Purity98%min
Supply Capacity
DetailsSonidegib (erismodegib or LDE225) is a Hedgehog signaling pathway inhibitor being developed as an anticancer agent. It has been investigated as a potential treatment for pancreatic cancer,breast cancer,basal cell carcinoma of the skin,small cell lung cancer,medulloblastoma,advanced solid tumours (including ovarian, breast, pancreatic, stomach, oesophageal cancers and glioblastoma multiforme),acute leukaemia,chronic myeloid leukaemia,myelofibrosis and essential thrombocythaemia .It has demonstrated significant efficacy against melanoma in vitro and in vivo. It also demonstrated efficacy in a mouse model of pancreatic cancer.

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