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Bioactive Molecules

Cabozantinib CAS:849217-68-1

Cabozantinib  CAS:849217-68-1


Product Information

CAS NO.849217-68-1 5.png
Product NameCabozantinib
SynonymsXL-184
FormulaC28H24FN3O5
Molecular Weight502
Spec / Purity98%min
Supply Capacity
DetailsCabozantinib( XL-184) is a small molecule inhibitor of the tyrosine kinases c-Met and VEGFR2, and has been shown to reduce tumor growth, metastasis, and angiogenesis.Cabozantinib was granted orphan drug status by the U.S. Food and Drug Administration (FDA) in January 2011.Cabozantinib was approved by the U.S. FDA in November 2012 for the treatment of medullary thyroid cancer. It is currently undergoing clinical trials for the treatment of prostate, bladder, ovarian, brain, melanoma, breast, non-small cell lung, pancreatic, hepatocellular and kidney cancers.

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