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Bioactive Molecules

Sapacitabine CAS:151823-14-2

Sapacitabine  CAS:151823-14-2

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Product Information

CAS NO.151823-14-2 
Product NameSapacitabine
SynonymsCS-682
FormulaC26H42N4O5
Molecular Weight490.63
Spec / Purity98%min
Supply Capacity
DetailsSapacitabine is a drug undergoing research for potential use in chemotherapy.Sapacitabine is an oral nucleoside analog prodrug that acts through a dual mechanism. The compound interferes with DNA synthesis by causing single-strand DNA breaks and induces arrest of the cell division cycle at G2 phase. Both sapacitabine and its major metabolite, CNDAC, have demonstrated potent anti-tumor activity in both blood and solid tumors in preclinical studies. In a liver metastatic mouse model, sapacitabine was shown to be superior to gemcitabine or 5-FU, two widely used nucleoside analogs, in delaying the onset and growth of liver metastasis.

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